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keloid fibroblasts were prone to senescence following an ischemic stimulus, and FOXO4-DRI selectively induced the apoptosis of keloid senescent fibroblasts via p53-pS15 translocation from the nucleus to the cytoplasm

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The technique is learnable, but the decisions around it (do you actually need it, what dose, how often, and is something else being missed) are medical judgements, and getting them wrong carries real cost